MoreiraEstes3

De Communautique.

Signs of serotonin syndrome'

Irritability, Craze, Change, Fits, Restlessness, Increased middle rate, Sweating, Chill, Tremor, Cerebral status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Shaking, Pain in the abdomen, Diarrhea, Perspiration, Increased temperature, Hypertension. All these are symptoms of serotonin syndrome. Almost all can come usually inside the first day after taking a particular o.d. of serotonin drugs. This symptoms are on mental processes level, autonomic degree as well as somatic degree. Serotonin toxicity come usually after o.d. of serotonin drugs and drug combination which increase synaptic serotonin. Drugs that are understand to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Pep pill, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Amphetamine. Due to the fact serotonin syndrome it's certainly not tested in the laboratory for diagnosis, signs or symptoms are the one need observed. The best set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome tend to be because follows: discontinuing drugs which made the o.d. posible as well as drugs which can lead management of serotonin antagonist (eg. cyproheptadine) for sever cases of toxicity for agitation, muscle stiffness as well as capture like movements, benzodiazepines (Valium, Ativan) Intra venous liquids Because serotonin syndrome is not simple to diagnose, prevention is wanted for any serotonin drugs mixture of that might lead to 5-hydroxytryptamine toxicity.

Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642 Prator BC. Serotonin syndrome symptoms. J Neurosci Nurs. 2006 Apr;38(2):102-5. Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.